主动脉瘤

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TUhjnbcbe - 2021/8/1 3:51:00

文章题目:

IdentificationofcrucialgenesinabdominalaorticaneurysmbyWGCNA

文章信息:

PeerJ.Oct8;7:e.

doi:10./peerj..eCollection

英文摘要:

Background:Abdominalaorticaneurysm(AAA)isthefullthicknessdilationoftheabdominalaorta.However,feweffectivemedicaltherapiesareavailable.Thus,elucidatingthemolecularmechanismofAAApathogenesisandexploringthepotentialmoleculartargetofmedicaltherapiesforAAAisofvitalimportance.

Methods:Threeexpressiondatasets(GSE,GSEandGSE)weredownloadedfromtheGeneExpressionOmnibus(GEO).Thesedatasetsweremergedandthennormalizedusingthe“sva”Rpackage.Differentialexpressedgene(DEG)analysisandweightedgeneco-expressionnetworkanalysis(WGCNA)wereconducted.We

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