文章题目:
IdentificationofcrucialgenesinabdominalaorticaneurysmbyWGCNA
文章信息:
PeerJ.Oct8;7:e.
doi:10./peerj..eCollection
英文摘要:
Background:Abdominalaorticaneurysm(AAA)isthefullthicknessdilationoftheabdominalaorta.However,feweffectivemedicaltherapiesareavailable.Thus,elucidatingthemolecularmechanismofAAApathogenesisandexploringthepotentialmoleculartargetofmedicaltherapiesforAAAisofvitalimportance.
Methods:Threeexpressiondatasets(GSE,GSEandGSE)weredownloadedfromtheGeneExpressionOmnibus(GEO).Thesedatasetsweremergedandthennormalizedusingthe“sva”Rpackage.Differentialexpressedgene(DEG)analysisandweightedgeneco-expressionnetworkanalysis(WGCNA)wereconducted.We