应用WGCNA技术筛选腹主动脉瘤关键基因 [复制链接]

文章题目：

IdentificationofcrucialgenesinabdominalaorticaneurysmbyWGCNA

文章信息：

PeerJ.Oct8;7:e.

doi:10./peerj..eCollection

英文摘要/p>

Background:Abdominalaorticaneurysm(AAA)isthefullthicknessdilationoftheabdominalaorta.However,feweffectivemedicaltherapiesareavailable.Thus,elucidatingthemolecularmechanismofAAApathogenesisandexploringthepotentialmoleculartargetofmedicaltherapiesforAAAisofvitalimportance.

Methodshreeexpressiondatasets(GSE,GSEandGSE)weredownloadedfromtheGeneExpressionOmnibus(GEO).Thesedatasetsweremergedandthennormalizedusingthe“sva”Rpackage.Differentialexpressedgene(DEG)analysisandweightedgeneco-expressionnetworkanalysis(WGCNA)wereconducted.We